Comparative Morphology of Microchips Assmebled in Dental Anaesthetics Lidocaine and Carbocaine.

Many similarities. Both are products of Abbot Pharma, from currently circulating lots. Minor differences might or might not be clinically and functionally significant.

After studying Carbocaine in a variety of experiments, I turned to Lidocaine, another injectable dental anaesthetic from the same manufacturer. I used the identical slide preparation technique, and detected very similar looking “microchips” that are allegedly self-assembled from nano-building blocks present in the products. Magnification 100-200x, phase-contrast (difference in color is due to trying different filters, which they did not result in drastic difference in the images).

The last two side-by-side images confidenlty demonstrate the distinction in morphology that I picked up on: the sides and corners of the microchips in Lidocaine are enforced/accentuated, - more so than in Carbocaine.

I don’t suspect there is any deep significance to this feature, but it speaks to the lack of homogeneity of structures formed in various pharmaceutical products. Spectral analysis would be extremely useful. Based on seeing bright luminescent structures, it would be prudent to hypothesize the presence of metallic semiconductor nano-materials in both pharmaceutical injectable dental anesthetics.

Thank you!